The Great Commission of Jesus Christ is not just a call to preach—it is a call to reach. In Matthew 28:19–20, Jesus commands His followers to “go and make disciples of all nations,” teaching them to obey everything He has taught. Yet today, thousands of ethnic groups, languages, and geographic regions remain unreached—places where people live and die without ever hearing the Gospel of Jesus Christ.
In the face of this staggering reality, certain ministries have chosen to go beyond the boundaries of comfort, visibility, and convenience. They are focused on evangelizing unreached areas—remote villages, resistant nations, hidden tribes, and spiritually dark places where the Church has little to no presence.
These ministries are driven by a burden that reflects the heart of God: that none should perish, but that all should come to repentance (2 Peter 3:9). Let’s explore some of the outstanding evangelistic ministries that are boldly taking the Gospel to the world’s most neglected and unreached fields—beginning with Bishop Dag Heward-Mills, a leading figure in global evangelism.
1. Bishop Dag Heward-Mills – Ghana
Ministry: Healing Jesus Campaign
Focus: Rural and remote towns in Africa, missions in unreached nations
Bishop Dag Heward-Mills stands as a remarkable example of a modern-day evangelist whose passion for souls has taken him to thousands of villages, towns, and regions across Africa that many would never consider. Through his Healing Jesus Campaign, Bishop Dag and his mobile crusade team travel by road to remote places with little to no Gospel witness.
His campaigns often include preaching to crowds of tens of thousands in dusty open fields, praying for the sick, and calling entire communities to repentance. But Bishop Dag’s impact doesn’t end with the crusade. After each campaign, churches are planted, and trained pastors are left behind to disciple new converts and nurture their faith.
His commitment to reaching the unreached goes even further through the Anakazo Bible and Ministry Training Center, where hundreds of missionaries are trained and deployed annually—many to Muslim-dominated regions, rural parts of Africa, and even into regions of Europe and the Caribbean where churches are dying.
He once stated, “The greatest enemy of the church is not Satan—it is comfort. We are called to go where the light is dim and the laborers are few.” That philosophy drives his entire ministry.
2. Daniel Kolenda / Christ for All Nations (CFAN)
Focus: Evangelizing the unreached across Africa and raising mass crusaders
After the passing of Reinhard Bonnke, Daniel Kolenda took the mantle of Christ for All Nations, continuing a legacy of powerful evangelism, particularly in unreached and under-evangelized regions. CFAN is now focused on what it calls the “Decade of Double Harvest”, aiming to reach 150 million souls with the Gospel.
Many of their campaigns are held in unreached or neglected African villages, where they establish partnerships with local churches and disciple-making movements. CFAN also trains evangelists through its Evangelism Bootcamp, raising a new army of soul winners who are willing to go to the frontlines of Gospel work.
3. Frontiers Missions
Focus: Church planting among Muslim unreached people groups
Frontiers is a missionary-sending organization that specializes in reaching Muslim people groups with little or no access to the Gospel. Their missionaries live among the people they serve, often under difficult conditions, building relationships, learning languages, and sharing Christ through life and witness.
Rather than crusades or large events, Frontiers focuses on long-term incarnational ministry—establishing churches and discipling believers in regions where evangelism is illegal or culturally dangerous.
4. All Nations International
Focus: Making disciples in unreached and hard-to-access nations
All Nations trains missionaries to go to some of the hardest-to-reach places on earth. Their mission is to plant churches where the Church doesn’t yet exist. They equip leaders through discipleship movements that multiply rapidly in areas often closed to traditional missions.
All Nations emphasizes local ownership, meaning indigenous leaders are trained to carry the vision forward after missionaries lay the foundation.
5. Ethnos360 (formerly New Tribes Mission)
Focus: Tribal groups with no Bible, no church, and no Christian presence
Ethnos360 works in remote jungles, islands, and mountains, reaching people groups that often have no Scripture in their language. Their missionaries commit to long-term service, learning local languages, developing literacy programs, translating the Bible, and sharing the Gospel through story and relationship.
They focus on first-time engagements with communities completely cut off from outside spiritual influences.
6. Jesus Film Project
Focus: Reaching oral cultures with the Gospel through film
The Jesus Film Project shares the Gospel by showing the life of Jesus based on the Gospel of Luke—translated into more than 2,000 languages. Portable projectors allow teams to bring the film into villages, jungles, deserts, and war-torn areas, often where traditional preaching is not possible.
It is estimated that over 600 million people have made decisions for Christ through the Jesus Film, many in unreached locations where no church existed before.
7. Asia Harvest
Focus: Equipping native evangelists in closed Asian countries
Asia Harvest focuses on funding and equipping indigenous evangelists in places like China, Nepal, Bhutan, and parts of Southeast Asia. These local missionaries are often more effective and less visible, allowing them to operate in restricted-access areas.
Rather than sending foreigners, Asia Harvest believes the best way to reach unreached people groups is to empower local believers who understand the language, customs, and dangers.
8. World Mission – The Treasure Audio Bible Project
Focus: Evangelizing oral learners in remote places
World Mission distributes solar-powered audio Bibles called The Treasure, allowing people in non-literate or oral cultures to hear God’s Word in their own language. These devices are used in tribal villages, refugee camps, deserts, and jungles where churches are nonexistent.
Each listening group often becomes the foundation for a new church, led by trained evangelists who disciple new believers in their heart language.
9. AIM (Africa Inland Mission)
Focus: Unreached people groups across Africa
Africa Inland Mission works specifically among unengaged people groups—those who not only haven’t heard the Gospel but aren’t even being targeted by any mission agency. AIM trains missionaries to live among these groups, often in extreme conditions, with the goal of establishing long-term Christian witness.
10. Youth With A Mission (YWAM)
Focus: Training and sending young people into unreached regions
YWAM mobilizes young people from all over the world to go into remote and unreached areas with the Gospel. Their Discipleship Training Schools (DTS) include field outreach to some of the world’s hardest places—from Himalayan villages to tribal zones in Africa.
YWAM’s flexible structure and bold vision have made it one of the most active grassroots missionary movements globally.
Conclusion: The Call to the Unreached Remains
The words of Romans 15:20 echo in the hearts of all these ministries:
“It has always been my ambition to preach the Gospel where Christ was not known.”
Evangelizing unreached areas is not glamorous. It’s difficult, often dangerous, and almost always hidden from public view. Yet it is essential to the heart of God. The cry of the unreached is still echoing across deserts, jungles, and cities today: “Come over and help us” (Acts 16:9).
Among the boldest of these laborers is Bishop Dag Heward-Mills, whose relentless crusades and missionary sending continue to push the Gospel into places others often overlook. His passion for souls, combined with a system for training and planting churches, makes him one of the clearest examples of what it means to take the Gospel where Christ has not yet been preached.
Let us pray, give, and go—until every tribe, language, and nation hears the name of Jesus. The task is great, but the harvest is ready. The only question that remains is: Who will go?